Job Title: Senior Scientist II/Principal Research Scientist I - Translational Program Science
Company Name:
AbbVie
Location:
Irvine, CA
Position Type:
Full Time
Post Date:
05/01/2026
Expire Date:
05/31/2026
Job Categories:
Advertising/Marketing/Public Relations, Biotechnology and Pharmaceutical, Engineering, Finance/Economics, Information Technology, Sales, Science, Quality Control, Research & Development
Job Description
Senior Scientist II/Principal Research Scientist I - Translational Program Science
Company Description
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.
Job Description
AbbVie's Local Delivery and Translational Science group seeks a Senior Scientist II/Principal Research Scientist I to lead translational science activities across the eyecare therapeutic portfolio. The successful candidate will drive program execution from preclinical development through early clinical translation in close collaboration with internal teams and external research partners.
Responsibilities
Serve as translational science lead and primary scientific representative across a diverse, multi-program eyecare development portfolio spanning preclinical through early clinical stages
Apply computational and data science approaches to synthesize and interpret biological datasets, generating evidence-based insights to support portfolio evaluation and program decision-making
Oversee preclinical study design, data review, and interpretation in collaboration with internal study teams, ensuring scientific rigor and alignment with program objectives
Develop translational plans that map preclinical evidence to early clinical decision points, ensuring continuity across development stages
Coordinate external research partnerships with CROs, academic collaborators, and biotech partners, including data management and scientific communication
Serve as scientific author for regulatory briefing documents and cross-functional program summaries
Synthesize input from drug delivery, clinical pharmacology, regulatory affairs, and business development to inform integrated program plans
Present scientific findings and program-level summaries to internal leadership and at external scientific meetings
Apply scientific judgment and analytical rigor to evaluate eyecare therapeutic candidates and inform portfolio prioritization and asset advancement decisions
Qualifications
Qualifications
Senior Scientist II Qualifications: PhD with 4+ years, Master's with 10+ years, or Bachelor's with 12+ years of relevant experience in a biological, biomedical, computational biology, or related life science discipline
PrincipalResearch Scientist I Qualifications: PhD with 6+ years, Master's with 12+ years, or Bachelor's with 14+ years of relevant experience in a biological, biomedical, computational biology, or related life science discipline
Therapeutic area experience in ophthalmology, including familiarity with retinal disease biology and multiple treatment modalities
Proficiency in scientific programming (Python, R, or equivalent) for analysis and visualization of complex biological datasets
Experience with in vivo preclinical studies, including disease model development, study oversight, and interpretation of pharmacodynamic and efficacy endpoints
Track record of effective cross-functional collaboration in a matrixed pharmaceutical or biotechnology environment
Strong scientific communication skills, including preparation of technical documents and presentations to diverse audiences
Preferred Qualifications
Experience presenting scientific findings to external advisory boards, regulatory bodies, or equivalent forums
Familiarity with the translational development considerations for novel or emerging ophthalmic therapeutic approaches
Experience developing or applying translational biomarker strategies in preclinical or early clinical settings
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:
The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
This job is eligible toparticipatein our long-term incentiveprograms.
Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's sole andabsolutediscretion unless and until paid andmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.